Hello Reclone Community 
To kick off our Community Meetings this year, we invite you all to join us on 2025-01-29T14:00:00Z. We will hear from @Aubin, presenting about Advancing Nanobody Discovery and Engineering with Machine Learning.
Nanobodies, or single-domain antibodies, are small antibody fragments naturally expressed in camelids, characterised by their high expressibility, solubility and stability alongside an affinity comparable to full-length antibodies. They have gained significant momentum since the approval of the first nanobody drug in 2019, yet the development of these biologics as therapeutics remains a challenge. Despite the availability of established in vitro directed-evolution technologies that are relatively fast and cheap to deploy, the gold standard for generating therapeutic antibodies with favourable properties in vivo remains discovery from animal immunisation or patients. This raises the question of whether a computational design strategy will ever meet the challenge of generating fully functional and developable antibodies in silico.
Join us via Zoom: Launch Meeting - Zoom
Feel free to invite and share news to others in your networks who might be interested 
You can also check our previous meetings at Events – Reagent Collaboration Network or via the Reclone YouTube channel.
Likewise, you can see the Upcoming Events on the Reclone Calendar, tell us you’re Interested/Going, and add these to your own calendar.
See you all next week!
