Here is the complete Abstract for the talk:
This Reclone meeting will discuss a first of its kind study in Syria that revolved asthma genetics and involved a case-control study. The rs2280091 T1 polymorphism in the ADAM33 gene was evaluated using PCR-RFLP technology (genetic fingerprint), with using minimal resources and many unusual methods to overcome the micro and macro difficulties faced in this study.
This research found statistically significant associations between eosinophil count, weight, familial asthma, and FEV1 difference before and after the reversibility test with condition. The polymorphic genotype in locus rs2280091 was also found to be statistically associated with asthma severity, with genotype G/G being associated with increased severity and decreased FEV1.
The genetic pool in Aleppo city (with a single genotype indicator) was found to be rich in diversity in the light of heterozygous type dominance over other genotypes, indicating the need for further research.